FIG 1.

In the control group, no mice had MEE. In the COM group, MEE was induced in all mice that received an NTHi injection and ET obstruction (A). All MEEs were purulent at day 3 after inoculation, and 71% were purulent at 2 weeks. At 1 month (1M) after inoculation, the ratio of mucoid effusions was increased to 70%. At 2 months (2M) after inoculation, 50% of MEEs had become serous and 38% of effusions had become pultaceous (B). ND, not detected.