TABLE 3.
Average frequencies of CD4, CD8, and regulatory T cells in the middle ear
| Groupa | Frequency of cells: |
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|---|---|---|---|---|---|
| CD3+ |
CD4+b |
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| % CD4 | % CD8 | CD4/CD8 ratio | % FoxP3+ | % CD25+ FoxP3+ | |
| Control | 42.8 ± 15.6 | 17.7 ± 11 | 2.7 ± 1.2 | 18.5 ± 1.3 | 12.2 ± 2.4 |
| Day 3 | 40.2 ± 8.3 | 10.0 ± 2.1 | 4.0 ± 0.2 | 15.4 ± 4.5 | 10.6 ± 1.8 |
| Day 14 | 30.8 ± 8.6 | 12.8 ± 1.5 | 2.4 ± 0.6 | 45.0 ± 4.0* | 38.3 ± 4.9* |
| 1 mo | 33.7 ± 11.0 | 8.4 ± 4.7 | 4.6 ± 1.6 | 40.3 ± 1.8* | 34.7 ± 2.0* |
| 2 mo | 33.6 ± 8.6 | 7.3 ± 2.3 | 4.8 ± 1.2 | 34.4 ± 2.5* | 27.8 ± 2.3* |
a
MNCs were collected from 5 mice. This experiment was performed independently 3 times.
b
*, P < 0.05 compared to control by Mann-Whitney test.