Table 3.

SMC miR function and targets

miR	Function	Target mRNA	Species	References
1	↓ SMC proliferation	PIM1	Hsa	[118]
1	↑ SMC differentiation in ES cells	Klf4	Mmu	[119]
10a	↑ SMC differentiation in ES cells	Hdac4	Mmu	[139]
124	↓ SMC proliferation/↑ SMC differentiation	Nfatc1	Hsa	[235]
125b	↑ SMC inflammation	Suv39h1	Mmu	[236]
130a	↑ SMC proliferation	Meox1	Rno	[113]
132	↓ SMC proliferation/↓ neointima	Lrrfip1	Rno	[237]
133a	↓ SMC proliferation/↓ SMC migration	Sp1	Rno	[124]
138	↓ SMC apoptosis	Mst1	Rno	[238]
143/145	↓ SMC proliferation/↑ SMC differentiation	Kfl4/Elk1/Camk2d	Mmu	[128]
143/145	↑ SMC differentiation/↓ neointima	Kfl5	Rno	[132]
143/145	Cytoskeletal dynamics	Klf4/Klf5/Add3	Mmu	[129]
146a	↑ SMC proliferation/↑ neointima	Kfl4	Rno	[112]
195	↓ SMC proliferation/↓ SMC migration	CDC42/CCND1	Hsa	[239]
200	↑ SMC inflammation in diabetes	Zeb1	Mmu	[114]
204	↓ SMC proliferation/↑ SMC apoptosis	SHP2	Hsa	[240]
205	↓ SMC calcification	Runx2	Hsa	[241]
206	↓ SMC proliferation/↑ SMC differentiation	Notch3	Hsa	[242]
21	↑ SMC differentiation	PDCD4	Hsa	[109]
21	↓ SMC differentiation/↑ neointima	Pten	Rno	[108]
210	↓ SMC apoptosis	E2F3	Hsa	[243]
221/222	↑ SMC proliferation/↓ SMC differentiation	KIT/CDKN1B	Hsa	[110]
221/222	↑ SMC proliferation/↑ neointima	Cdkn1b/Cdkn1c	Rno	[111]
22	↑ SMC differentiation	Mecp2	Mmu	[244]
224	?	TCF21	Hsa	[168]
24	↓ SMC inflammation/↓ SMC migration	CHI3L1	Hsa	[115]
26a	↑ SMC proliferation/↓ SMC differentiation	SMAD1	Hsa	[141]
29a	↓ SMC migration	Pdgfrb	Mmu	[126]
30b/30c	↓ SMC calcification	RUNX2	Hsa	[116]
31	↑ SMC proliferation	Lats2	Rno	[245]
31	↓ SMC differentiation	CREG	Hsa	[246]
322	↓ SMC proliferation/↓ SMC migration	Ccnd1/Ppp3 cc	Rno	[247]
34a	↑ SMC differentiation	Sirt1	Mmu	[135]
365	↓ SMC proliferation	Ccnd1	Rno	[248]
638	↓ SMC proliferation/↓ SMC migration	NR4A3	Hsa	[249]
663	↓ SMC proliferation/↑ SMC differentiation	JUNB	Hsa	[250]
96	↓ SMC differentiation	TRB3	Hsa	[251]
Let7a	↓ SMC proliferation/↓ SMC migration	Myc/Kras	Rno	[252]