. 2015 Nov 14;7(11):974–985. doi: 10.18632/aging.100844

Table 2. Transcriptional gene regulation in skeletal progenitors overexpressing Btg2 gene (hBtg2) and Btg2 in combination with sh-p21 (hBtg2 + sh-p21) compared with control cells transfected with empty vectors.

Gene	GenBank	hBtg2(Fold changes vs Control)	hBtg2 + sh-p21(Fold changes vs Control)
Cell Cycle Regulation
*p21*	AF513031	3.24 ± 0.63^**	0.54 ± 0.03 ^*** ^##
*p53*	NM_205264	1.06 ± 0.11	0.68 ± 0.04
*p63*	NM_204351	0.83 ± 0.05	0.74 ± 0.07
*p73*	XM_417545	0.94 ± 0.10	1.19 ± 0.14
*Bcl2*	NM_205339	0.58 ± 0.03^***	0.75 ± 0.04 ^##
*Bak*	NM_001030920	3.20 ± 0.97^*	3.81 ± 0.16^*
*MAFA*	NM_205025	2.57 ± 0.17^***	1.48 ± 0.14 ^* ^###
*MAFB*	NM_001030852	1.64 ± 0.16^**	1.18 ± 0.10 ^#
*IL8L1*	NM_205018	6.36 ± 1.00^***	3.24 ± 0.35 ^** ^#
*IL8L2*	NM_205498	6.07 ± 1.58^**	6.42 ± 1.03^**
*AREGB*	NM_001031537	3.01 ± 0.44^***	1.76 ± 0.29^* ^#
*HGF*	NM_001030370	5.46 ± 0.56^***	3.00 ± 0.16 ^** ^##
TGFβ2	XM_003640970	2.00 ± 0.35^*	0.91 ± 0.05 ^#
*IGF1*	NM_001004384	4.16 ± 0.58^***	2.16 ± 0.14^** ^#
*IGFBP5*	XM_004942886	0.75 ± 0.07	0.62 ± 0.03
*MMP2*	NM_204420	1.52 ± 0.15^*	1.56 ± 0.04^**
*MMP9*	NM_204667	1.46 ± 0.13^*	1.29 ± 0.13
*Adamts9*	XM_414417	1.05 ± 0.08	1.46 ± 0.11 ^* ^##
*FAS*	XM_421659	2.39 ± 0.42^**	1.53 ± 0.12 ^** ^#
*FASLG*	NM_001031559	1.11 ± 0.14	0.98 ± 0.13
*TNFRSF21*	NM_001031103	1.95 ± 0.29^**	0.94 ± 0.10 ^##
*TNFRSF23*	NM_204386	1.02 ± 0.11	0.77 ± 0.11

^***

p < 0,001;

^**

p < 0.01;

p< 0.05 statistical significance vs control cells;

^###

p< 0,001;

^##

p < 0.01;

p< 0.05 statistical significance vs hBtg2.