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(A) Matrix stiffness alters the pericellular matrix and subsequently the chondrogenic response of MSCs to HP (Steward et al. 2013). Reproduced with kind permission from eCM journal (www.ecmjournal.org). (B) DC can override local substrate cues to switch MSCs from a myogenic to chondrogenic state (FS = free swelling; Thorpe et al. 2012). Reproduced with kind permission from Elsevier.
