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. 2015 Aug 11;3(6):558–569. doi: 10.1002/mgg3.168

Table 2.

Selected genotyping results. (A) Comparisons relative to NAFLD cases. (B) comparisons relative to sample Bronx population

(A)
Gene SNP MAF‐NAFLD cases MAF‐controls OR P‐value MAF‐Bronx population OR P‐value MAF‐general population RR P‐value MAF‐Puerto Rican population OR P‐value
CHUK rs11597086 26% (22/15/3) 16% (15/7/0) 1.65 0.35 23% (134/75/14) 1.14 0.67 22% (694/308/90) 1.18 0.55 43% (19/25/11) 0.61 0.09
ENPP1 rs1044498 37% (19/11/9) 42% (10/8/6) 0.89 0.72 36% (105/80/42) 1.03 0.90 29% (660/224/208) 1.27 0.29 19% (37/15/3) 1.96 0.05
ERLIN1 rs2862954 29% (20/14/4) 14% (15/6/0) 2.03 0.20 26% (127/69/22) 1.12 0.70 25% (665/314/113) 1.17 0.55 48% (15/27/13) 0.60 0.07
PNPLA3 rs738409 56% (9/17/14) 19% (16/7/1) 2.95 0.003 19% (139/62/8) 3.01 4.4E‐7 28% (590/382/120) 1.97 0.0001 36% (20/30/5) 1.56 0.05
PNPLA3 rs2896019 41% (17/13/10) 17% (17/6/1) 2.48 0.04 25% (132/75/20) 1.63 0.04 28% (604/374/114) 1.50 0.06 28% (27/25/3) 1.47 0.18
SAMM50 rs3761472 38% (17/14/8) 17% (16/8/0) 2.31 0.07 21% (146/68/14) 1.83 0.02 25% (628/374/90) 1.52 0.07 21% (33/21/1) 1.83 0.06
SAMM50 rs2143571 44% (14/16/9) 25% (13/10/1) 1.74 0.14 28% (120/88/20) 1.55 0.05 32% (514/453/125) 1.35 0.14 30% (25/27/3) 1.45 0.18
ABCC2 rs17222723 10% (31/8/0) 2% (23/1/0) 4.92 0.22 7% (193/33/0) 1.40 0.52 4% (1000/91/1) 2.40 0.08 7% (47/8/0) 1.47 0.57
(B)
MAF‐Bronx population MAF‐general population OR P‐value MAF‐Puerto Rican population OR P‐value
CHUK rs11597086 23% 22% 1.04 0.79 43% 0.54 0.003
ENPP1 rs1044498 36% 29% 1.24 0.04 19% 1.90 0.02
ERLIN1 rs2862954 26% 25% 1.05 0.69 48% 0.54 1.5E‐3
PNPLA3 rs738409 19% 28% 0.66 3.5E‐3 36% 0.52 5.2E‐4
PNPLA3 rs2896019 25% 28% 0.92 0.49 28% 0.90 0.68
SAMM50 rs3761472 21% 25% 0.83 0.17 21% 1.00 0.98
SAMM50 rs2143571 28% 32% 0.87 0.22 30% 0.94 0.78
ABCC2 rs17222723 7% 4% 1.71 0.05 7% 1.04 0.94

NAFLD, nonalcoholic fatty liver disease; SNP, single‐nucleotide polymorphisms.