Table 3.

PNPLA3 sequencing results (all P‐values are for relative comparisons to NAFLD cases)

SNP	NAFLD allele frequency n = 40	Control allele frequency n = 24	P	OR	Minor allele	Chromosome position	MAF n = 2184	P	MAF (HIS) n = 362	P	MAF (PUR) n = 110	P
rs738409	56%	19%	0.003	3.00	G	43,928,847	28.4%	1.18E‐04	45%	0.18	36%	0.03
rs738408	55%	19%	0.004	2.93	T	43,928,850	28.4%	2.35E‐04	45%	0.23	36%	0.04
rs2294919	10%	30%	0.040	0.33	T	43,946,445	26.1%	0.02	19%	0.16	19%	0.19
rs4823173	41%	19%	0.063	2.20	A	43,932,850	25.7%	0.03	39%	0.78	28%	0.12
rs139047	35%	14%	0.086	2.45	A	43,927,194	34.2%	0.92	25%	0.17	25%	0.23
rs2294918	20%	39%	0.112	0.52	A	43,946,236	23.0%	0.65	24%	0.57	31%	0.18
rs139051	54%	38%	0.208	1.43	A	43,928,796	47.8%	0.46	55%	0.88	45%	0.34
rs34879941	25%	8%	0.215	3.00	T	43,936,998	27.3%	0.75	40%	0.06	28%	0.72
rs41278873	10%	2%	0.246	4.60	C	43,946,811	3.0%	0.01	6%	0.33	9%	0.85
rs144730517	3%	0%	0.353	2.56a	G	43,944,762	0.1%	6.94E‐05	0%	0.00	0%	0.10
rs115043594	0%	2%	0.445	0.29	A	43,946,514	0.0%	NA	NA	NA	NA	NA
rs192841252	4%	0%	0.614	2.15	T	43,927,190	0.1%	1.85E‐08	1%	0.14	1%	0.25
rs2294917	16%	21%	0.652	0.77	C	43,946,106	35.2%	0.01	28%	0.11	29%	0.11
rs2076213	14%	10%	0.696	1.32	G	43,927,042	7.6%	0.15	17%	0.60	13%	0.90
rs41278871	3%	0%	0.743	1.68	C	43,946,775	0.6%	0.13	0%	0.00	0%	0.10
rs2072906	23%	18%	0.758	1.24	G	43,937,292	27.5%	0.48	40%	0.03	28%	0.50
rs2076212	14%	17%	0.760	0.83	T	43,927,090	11.0%	0.58	13%	0.89	15%	0.87
rs6006461	1%	0%	0.793	1.56	T	43,946,433	0.2%	0.78	0%	NA	0%	NA
rs76510336	3%	2%	0.797	1.55	G	43,946,295	1.4%	0.56	0%	0.00	1%	0.49
rs6006460	1%	2%	0.898	0.78	T	43,946,294	3.1%	0.26	0%	NA	0%	NA
rs144821153	1%	0%	0.908	1.22	G	43,923,872	0.4%	0.41	1%	0.88	1%	0.85
rs34179073	3%	2%	0.915	1.20	T	43,932,952	4.4%	0.56	7%	0.28	6%	0.39

NAFLD, nonalcoholic fatty liver disease; MAF, minor allele frequency; SNP, single‐nucleotide polymorphisms.

^aUsing zero‐cell correction.