TABLE 2 ] .

International Classification of Sleep Disorders, Third Edition, Diagnostic Criteria¹⁰

Narcolepsy Type 1a Criteria A and B	Narcolepsy Type 2b All Criteria A-E	Idiopathic Hypersomniac All Criteria A-F
A. Daily periods of irrepressible need to sleep or daytime lapses into sleep, present for at least 3 mo	A. Daily periods of irrepressible need to sleep or daytime lapses into sleep, present for at least 3 mo	A. Daily periods of irrepressible need to sleep or daytime lapses into sleep, present for at least 3 mo
B. Either 1 or 2 or both	B. Mean sleep latency ≤ 8 min and two or more SOREMPs on MSLT. REM within 15 min of sleep onset on the preceding nocturnal polysomnogram may replace one of the SOREMPs.	B. Fewer than two SOREMPs on MSLT (or fewer than one if nocturnal REM latency was ≤ 15 min)
1. Cataplexy and mean sleep latency ≤ 8 min and two or more SOREMPs on MSLT. REM within 15 min of sleep onset on the preceding nocturnal polysomnogram may replace one of the SOREMPs.	C. No cataplexy	C. No cataplexy
2. Low CSF hypocretin-1 concentration (< 110 pg/mL or less than one-third of control values)	D. CSF hypocretin-1 concentration has not been measured or CSF hypocretin-1 concentration is ≥ 110 pg/mL or greater than one-third of control values.	D. Either 1 or 2 or both
	E. The hypersomnolence and/or MSLT findings are not better explained by other causes.	1. Mean sleep latency ≤ 8 min on MSLT
		2. Total 24-h sleep time ≥ 660 min on 24-h polysomnographic monitoring or wrist actigraphy (averaged over ≥ 7 d)
		E. Insufficient sleep syndrome is ruled out.
		F. The hypersomnolence and/or MSLT findings are not better explained by other causes.

CSF = cerebral spinal fluid; MSLT = multiple sleep latency test; REM = rapid eye movement; SOREMP = sleep-onset rapid eye movement period.

^aFormerly narcolepsy with cataplexy.

^bFormerly narcolepsy without cataplexy.

^cFormerly idiopathic hypersomnia with long sleep time and without long sleep time.