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. 2015 Oct 15;8(10):17096–17101.

Table 2.

Overall analysis between MMP2 polymorphism (-735 C/T) and susceptibility of cancer

Genetic comparison Population OR (95% CI) P Heterogeneity Model

P I2
C vs. T All 0.98 (0.85-1.14) 0.80 <0.001 76.74 Random
Asian 0.93 (0.79-1.09) 0.37 <0.001 77.89 Random
Caucasian 1.26 (0.83-1.91) 0.27 0.03 65.60 Random
C/C+C/T vs. T/T All 0.95 (0.79-1.14) 0.58 0.29 14.40 Fixed
Asian 0.99 (0.81-1.20) 0.91 0.56 <0.001 Fixed
Caucasian 0.62 (0.34-1.16) 0.14 0.12 48.90 Fixed
C/C vs. C/T+T/T All 0.97 (0.81-1.16) 0.71 <0.001 78.20 Random
Asian 0.90 (0.74-1.09) 0.28 <0.001 79.26 Random
Caucasian 1.24 (1.01-1.53) 0.040 0.17 40.72 Fixed
C/C vs. C/T All 0.99 (0.80-1.15) 0.63 <0.001 76.41 Random
Asian 0.89 (0.73-1.07) 0.22 <0.001 76.84 Random
Caucasian 1.30 (1.05-1.62) 0.015 0.42 <0.001 Fixed
C/C vs. T/T All 0.90 (0.75-1.09) 0.29 0.12 30.71 Fixed
Asian 0.93 (0.76-1.14) 0.48 0.20 25.38 Fixed
Caucasian 0.66 (0.35-1.23) 0.19 0.12 48.76 Fixed

OR, odds ratio; Bold numbers indicant significant association with risk of cancer.