Table 2.

Quality assessment of the included RCTs

Study	Random allocation	Double-blind	Concealed allocation	Baseline features	Eligibility criteria	Loss to follow-up	Selection bias	Quality
Mitsuru Sasako	Yes	No	Yes	Yes	yes	Yes	No	Fair
Hulscher	Yes	No	Unknown	Yes	yes	Yes	No	Fair
Omloo	Yes	No	Unknown	Yes	yes	Yes	No	Fair