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The down-regulated expression of KAP1 could increase the sensibility of chemotherapeutic drug paclitaxel. A: Western blot showed that KAP1 down-regulated in SKOV3/paclitaxel cells; B: MTT cell proliferation assay demonstrated that down-regulated KAP1 expression could significantly increase the sensitivity of SKOV3/paclitaxel; C: Clonogenic survival assay showed 4-5-fold decrease in cell growth in SKOV3/pacliaxel cell line of stable KAP1 knockdown cells than control cells.
