Table 1.
Main characteristics of all studies included in the meta-analysis
| First author | Year | Country | Ethnicity | Controls source | Cases/Controls | Case | Control | A allele in controls (%) | HWE | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||||||
| GG | AG | AA | GG | AG | AA | ||||||||
| Shete (German) | 2009 | German | European | PB | 499/566 | 108 | 240 | 151 | 90 | 265 | 211 | 0.61 | 0.66 |
| Shete (Sweden) | 2009 | Sweden | European | PB | 632/770 | 157 | 325 | 150 | 168 | 379 | 223 | 0.54 | 0.77 |
| Shete (US) | 2009 | US | European | HB | 1247/2235 | 276 | 594 | 377 | 370 | 1083 | 782 | 0.59 | 0.88 |
| Shete (French) | 2009 | French | European | PB | 1352/1583 | 239 | 639 | 474 | 209 | 723 | 651 | 0.64 | 0.71 |
| Schoemaker (Denmark) | 2010 | Denmark | European | PB | 121/245 | 29 | 55 | 37 | 27 | 64 | 54 | 0.59 | 0.30 |
| Schoemaker (Sweden) | 2010 | Sweden | European | PB | 196/367 | 57 | 97 | 42 | 80 | 177 | 110 | 0.54 | 0.58 |
| Schoemaker (UK-North) | 2010 | UK | European | PB | 375/627 | 85 | 182 | 108 | 110 | 301 | 216 | 0.58 | 0.77 |
| Schoemaker (UK-South) | 2010 | UK | European | PB | 232/390 | 49 | 113 | 70 | 68 | 181 | 141 | 0.59 | 0.45 |
| Wang | 2011 | US | European | PB | 332/817 | 68 | 151 | 113 | 125 | 389 | 303 | 0.61 | 0.99 |
| Stefano | 2012 | US | European | HB | 849/1190 | 137 | 409 | 303 | 143 | 531 | 516 | 0.66 | 0.96 |
| Li | 2012 | China | Asian | PB | 226/251 | 15 | 72 | 139 | 15 | 84 | 152 | 0.77 | 0.46 |
| Safaeian | 2013 | US | European | HB | 810/3081 | 179 | 383 | 248 | 509 | 1460 | 1112 | 0.60 | 0.42 |
PB population-based, HB hospital-based, HWE P values for Hardy-Weinberg equilibrium for each study’s control group.