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Expression of Wnt5a, FZD5 and CaMKIIδ in LPS-stimulated RAW 264.7 cells following treatment with BML-111 and transfection of Wnt5a-pcDNA3.1. Lane 1, LPS; lane 2, BML-111; lane 3, BML-111+Wnt5a. #P<0.01 compared with LPS; @P<0.01 compared with BML-111. LPS, lipopolysaccharide; BML-111, 5(S), 6(R)-7-trihydroxymethyl heptanoate; FZD5, frizzled-5; CaMKIIδ, calcium/calmodulin-dependent protein kinase II delta.
