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. 2015 Oct 15;8(10):17922–17931.

Figure 4.

Figure 4

Thyroxine and donepezil regulated the mRNA expressions of syt-1 and SNAP-25 in the dorsal hippocampus of adult hypothyroid rats. Real-time RT-PCR analyzed the expressions of syt-1 (A) and SNAP-25 (B) mRNA in the dorsal hippocampus of CON, Hypo, T4, DON, and T4+DON groups (n=8). All data were presented as mean ± SEM. CON, Control group; Hypo, hypothyroid group; T4, hypothyroid rats treated with 5 µg T4/100 g BW; DON, hypothyroid rats treated with 0.005% (w/v) DON in drinking water; T4+DON, hypothyroid rats treated with 5 µg T4/100 g BW and 0.005% (w/v) DON in drinking water. *P<0.05, **P<0.01 vs. Control group.