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. 2015 Oct 15;8(10):18032–18040.

Figure 3.

Figure 3

YM155 significantly reverses DOX resistance in OS cells. A. Cell proliferation was assessed by MTT assay in MG63 and MG63/DOX cells after treated with YM155 or DOX alone or both. B. Cell colony formation was determined in MG63/DOX cells after treated with YM155 or DOX alone or both. C. Cell apoptosis was determined in MG63/DOX cells after treated with YM155 or DOX alone or both. D-F. Caspase-3, -8 and -9 activity in MG63/DOX were detected cells after treated with YM155 or DOX alone or both. *P<0.05, **P<0.01 compared to untreated group.