Figure 4.

Gene-interaction network. Red: up-regulated gene. Violet: down-regulated gene. Green: transcriptional factor. a: activation; a(-p): activation (dephosphorylation); a(ind): activation (indirect effect); a(+p): activation (phosphorylation); a(u): activation (ubiquination); b: binding/association; c: compound; c(a): compound (activation); disso: dissociation; ex: expression; ex(ind): expression (indirect effect); ind: indirect effect; inh: inhibition; inh(-p): inhibition (dephosphorylation); inh(ind): inhibition (indirect effect); inh(+p): inhibition (phosphorylation); inh(u): inhibition (ubiquination); m: missing interaction; p: phosphorylation; u: ubiquination; u(inh): ubiquination (inhibition).