Table 2.
Relationship between the expression of Cyclin D1 and immune indicators of breast cancer (%)
| N | Cyclin D1 (negative) | Cyclin D1 (weak positive) | Cyclin D1 (strong positive) | χ2 | P | |
|---|---|---|---|---|---|---|
| ERα | ||||||
| Strong positive | 77 | 12 (15.6) | 28 (36.4) | 37 (48.1) | 15.207 | 0.004 |
| Weak positive | 80 | 21 (26.3) | 43 (53.8) | 16 (20.0) | ||
| Negative | 69 | 19 (27.5) | 29 (42.0) | 21 (30.4) | ||
| PR | ||||||
| Strong positive | 51 | 15 (29.4) | 15 (29.4) | 21 (41.2) | 12.987 | 0.011 |
| Weak positive | 113 | 19 (16.8) | 63 (55.8) | 31 (27.4) | ||
| Negative | 62 | 18 (29.0) | 22 (35.5) | 22 (35.5) | ||
| Her-2 | ||||||
| Strong positive | 119 | 24 (20.2) | 49 (41.2) | 46 (38.7) | 12.286 | 0.015 |
| Weak positive | 42 | 15 (35.7) | 13 (31.0) | 14 (33.3) | ||
| Negative | 65 | 13 (20.0) | 38 (58.5) | 14 (21.5) | ||
| Luminal A type | 72 | 9 (25.7) | 30 (41.7) | 33 (48.5) | 13.437 | 0.037 |
| Luminal B type | 54 | 15 (42.9) | 25 (34.7) | 14 (20.6) | ||
| Her-2 overexpression type | 27 | 6 (17.1) | 13 (18.1) | 8 (11.8) | ||
| Basal like type | 22 | 13 (19.1) | 4 (5.6) | 5 (14.3) |
Note: Lumina A type: ERα+, PR+, and Her-2-; Lumina B type: ERα+, PR+, and Her-2+; Her-2 overexpression type: ERα-, PR-, and Her-2+; basal like type: ERα-, PR-, and Her-2-.