Table 2.
The correlation between the reduced E-cadherin expression and clinicopathologic parameters
| Clinicopathologic parameter | Literature number | Heterogeneity | Effect model | OR | 95% CI | P |
|---|---|---|---|---|---|---|
| LNM (+ vs. -) | 3 | No | Fixed model | 3.940 | 2.088-7.436 | 0.00 |
| P=0.493 | ||||||
| MI (≥1/2 vs. <1/2) | 6 | Yes | Random model | 1.785 | 1.089-2.925 | 0.021 |
| P=0.041 | ||||||
| FIGO stage (III+IV vs. I+II) | 6 | Yes | Random model | 3.769 | 1.812-7.844 | 0.00 |
| P=0.015 | ||||||
| Histological grade (G3 vs. G1+G2) | 7 | Yes | Random model | 3.44 | 1.827-6.476 | 0.00 |
| P=0.03 | ||||||
| Pathological type (Non-endometrioid vs. Endometrioid) | 6 | No | Fixed model | 3.75 | 2.557-5.52 | 0.00 |
| P=0.070 |
MI: myometrial invasion; LNM: lymph node metastasis; FIGO: International Federation of Gynecology and Obstetrics.