Table 3.

Maximum toxicity per patient with most common grade 3 or 4

Event	FOLFOXIR-Bev	XELOXIRI-Bev	P value
Neutropenia	32 (46.4%)	15 (21.7%)	0.002
Febrile neutropenia	8 (11.6%)	5 (7.2%)	0.382
Diarrhea	14 (20.3%)	7 (10.1%)	0.097
Stomatitis	9 (13.0%)	4 (5.8%)	0.145
Nausea	3 (4.3%)	2 (2.9%)	0.649
Vomiting	6 (8.7%)	2 (2.9%)	0.145
Asthenia	10 (14.5%)	6 (8.7%)	0.228
Peripheral neuropathy	11 (15.9%)	0	0.001
Hypertension	4 (5.8%)	1 (1.4%)	0.172
Venous thromboembolism	5 (7.2%)	4 (5.8%)	0.730
Serious adverse events	14 (20.3%)	12 (17.4%)	0.663