Table 4.
The comparisons of characteristics among the genotypes in CAD patients
| Apelin receptor (APJ) A445C gene polymorphism | ||||
|---|---|---|---|---|
|
|
||||
| AA | AC | CC | P-value | |
| Age (years) | 64.8 ± 1.50 | 62.8 ± 1.35 | 66.8 ± 3.29 | 0.325 |
| Height (cm) | 167.6 ± 0.89 | 169.9 ± 0.79 | 171.9 ± 1.96 | 0.090 |
| Weight (kg) | 75.3 ± 1.96a | 78.5 ± 1.14 | 80.3 ± 1.99a | 0.05 |
| BMI (kg/m2) | 26.9 ± 0.37 | 27.1 ± 0.35 | 27.2 ± 0.77 | 0.685 |
| SBP (mmHg) | 130.4± 1.93a | 132.0 ± 1.59 | 137.3 ± 3.92a | 0.115 |
| DBP (mmHg) | 77.0 ± 1.35a | 78.0 ± 1.04b | 86.6 ± 2.42a,b | 0.008 |
| TC (mmol/L) | 163.9 ± 5.24a | 181.0 ± 5.17a | 164.3 ± 14.9 | 0.097 |
| LDL-C (mmol/L) | 97.9 ± 4.29 | 109.9 ± 4.17 | 100.8 ± 9.37 | 0.206 |
| HDL-C (mmol/L) | 41.8 ± 1.31 | 42.7 ± 1.35 | 40.4 ± 3.98 | 0.401 |
| TG (mg/dL) | 160.2 ± 14.8 | 151.7 ± 9.00 | 157.3 ± 30.3 | 0.889 |
| FBG (mmol/L) | 122.7 ± 6.67 | 136.3 ± 9.05 | 114.7 ± 8.08 | 0.383 |
| BUN (mmol/L) | 37.8 ± 2.36 | 38.1 ± 2.91 | 35.5 ± 3.34 | 0.683 |
| Creatinine (mg/L) | 0.97 ± 0.08 | 0.91 ± 0.05 | 0.97 ± 0.05 | 0.375 |
P: Shows the differences between all groups (Kruskal Wallis test).
a
In each line, the difference between the means with same letters are significant, P ≤ 0.05 (Mann-Whitney U test).
b
In each line, the difference between the means with same letters are significant, P ≤ 0.05 (Mann-Whitney U test).
Abbreviations: BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; LDL-C, low density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TG, triglycerides; FBG, fasting blood glucose, BUN, blood urea nitrogen.