Table 1.
Correlation between serum IL-35 levels and clinicopathological features of 132 ccRCC patients
| Characteristics | Case n (%) | Mean ± SD (pg/ml) | P value |
|---|---|---|---|
| Age (years) | |||
| ≤50 | 50 (37.8) | 25.11±12.07 | 0.742 |
| >50 | 72 (62.2) | 26.29±11.22 | |
| Gender | |||
| Male | 81 (61.4) | 27.27±12.27 | 0.311 |
| Female | 51 (38.6) | 23.14±10.36 | |
| Pathologic stage | |||
| I | 78 (59.1) | 12.04±6.89 | <0.001 |
| II | 32 (24.2) | 16.37±8.27 | |
| III | 12 (9.1) | 23.97±12.10 | |
| IV | 10 (7.6) | 29.14±10.24 | |
| Fuhrman Grade | |||
| I | 37 (28) | 15.17±9.14 | <0.001 |
| II | 77 (58.3) | 17.24±9.27 | |
| III | 12 (9.1) | 24.74±11.11 | |
| IV | 6 (4.6) | 28.04±12.34 | |
| Tumor size (cm) | |||
| ≤7 | 100 (75.8) | 22.14±11.09 | 0.012 |
| >7 | 32 (24.2) | 30.07±12.37 | |
| T stage | |||
| T1 | 85 (64.4) | 20.33±9.41 | 0.007 |
| T2 | 30 (22.7) | 26.29±12.17 | |
| T3, T4 | 17 (12.9) | 30.30±13.07 | |
| N stage | |||
| N0 | 113 (37.8) | 23.17±10.39 | 0.002 |
| N+ | 19 (37.8) | 31.34±13.27 | |
| Metastasis | |||
| No | 112 (85.6) | 21.97±10.11 | <0.001 |
| Yes | 20 (14.4) | 32.04±11.77 | |
| Recurrence | |||
| No | 110 (83.3) | 24.20±11.11 | 0.001 |
| Yes | 22 (16.7) | 29.87±13.04 |