Table 2.

Protection effect of polyphylla saponin I on mice infected with influenza A virus

Groups	Mortality (n)	Survival time (days)	Prolonged life rate (%)
Normal control	0	14	100
Influenza A virus infection	8	8.5±0.3
Oseltamivir (3 mg/kg)	2	12.1±0.7##	42.3
Polyphylla saponin I (5 mg/kg)	2	12.7±0.4##	49.4*
Polyphylla saponin I (10 mg/kg)	2	13.2±0.5##	55.3**

Note: The mice infected with influenza A virus were given polyphylla saponin I (5 and 10 mg/kg), or oseltamivir (3 mg/kg), twice a day, for 5 days. On the 14th day, the mortality and survival time of these mice were calculated. Prolonged life rate (%) = (Survival time of drug group-survival time of model control group)/survival time of model control group × 100%.

^##P<0.01 compared with influenza A virus infection group;

^**P<0.01 compared with oseltamivir group;

^*P<0.05 compared with oseltamivir group.