Table 1.
Baseline characteristics of 165 study subjects
| Group A (n = 40) | Group B (n = 45) | Group C (n = 80) | |
|---|---|---|---|
| Age (years) | 55.28 ± 12.01 | 57.18 ± 7.06 | 52.10 ± 10.31 |
| BMI (kg/m2) | 24.2 ± 2.11 | 25.47 ± 3.32 | 23.73 ± 1.78 |
| Hypertension, n (%) | 39 (97.5) | 43 (95.6) | 79 (98.8) |
| TC (mmol/L) | 2.44 ± 1.50 | 2.36 ± 1.02 | 2.19 ± 0.39 |
| TG (mmol/L) | 1.77 ± 0.89 | 1.61 ± 0.71 | 1.57 ± 0.86 |
| LDL-C (mmol/L) | 2.87 ± 0.79 | 2.77 ± 1.80 | 2.48 ± 0.94 |
| HDL-C (mmol/L) | 1.13 ± 0.19 | 1.26 ± 0.25 | 1.19 ± 0.38 |
| HbA1c (%) | 7.58 ± 1.18a,b | 5.84 ± 0.31a | 4.68 ± 0.24 |
| VE-cadherin (ug/ml) | 1.87 ± 0.14a,b | 1.77 ± 0.11a | 1.66 ± 0.17 |
| ET (pg/ml) | 49.94 ± 5.92a,b | 46.44 ± 1.59a | 44.37 ± 3.20 |
| NO (umol/L) | 37.56 ± 4.10a,b | 45.13 ± 13.20a | 53.21 ± 6.95 |
| NOS (umol/L) | 13.97 ± 3.71a,b | 16.75 ± 3.10a | 21.8 ± 8.18 |
Data are expressed as mean ± S.D. Abbreiations: BMI, body mass index; TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; HbA1c, hemoglobin A1c; ET-1, endothelin; NO, nitric oxide; NOS, nitric oxide synthase.
a
Compared with group C, P < 0.05;
b
Compared with group B, P < 0.05.
Group A: T2DM patients with coronary artery disease, Group B: T2DM patients without coronary artery disease or other complications, Group C: Chinese healthy subjects.