Table 1.
Normal hMLH1 (n=271) | Aberrant hMLH1 (n=56) | Total (n=327) | χ2 | P-value | |
---|---|---|---|---|---|
Age (years) | 0.439 | 0.507 | |||
<50 | 66 | 16 | 82 | ||
≥50 | 205 | 40 | 245 | ||
Gender | 0.184 | 0.668 | |||
Male | 168 | 33 | 201 | ||
Female | 103 | 23 | 126 | ||
Nationality | 1.109 | 0.775 | |||
Han | 226 | 49 | 275 | ||
Uyghur | 26 | 4 | 30 | ||
Hui | 11 | 1 | 12 | ||
Others | 8 | 2 | 10 | ||
Tumor location | 14.486 | 0.001 | |||
Right hemicolon | 46 | 22 | 68 | ||
Left hemicolon | 88 | 11 | 99 | ||
Rectal | 137 | 23 | 160 | ||
Tumor size (cm) | 1.906 | 0.386 | |||
<4 | 100 | 19 | 119 | ||
4-6 | 103 | 18 | 121 | ||
≥6 | 68 | 19 | 87 | ||
Tissue type | 10.487 | 0.005 | |||
Glandular (well/moderately) | 191 | 27 | 218 | ||
Glandular (poorly) | 33 | 11 | 44 | ||
Mucous gland/signet cell | 47 | 18 | 65 | ||
TNM staging | 12.508 | 0.006 | |||
I | 26 | 5 | 31 | ||
II | 79 | 29 | 108 | ||
III | 130 | 20 | 150 | ||
IV | 36 | 2 | 38 | ||
T staging | 1.620 | 0.655 | |||
T1 | 15 | 2 | 17 | ||
T2 | 32 | 6 | 38 | ||
T3 | 62 | 17 | 79 | ||
T4 | 162 | 31 | 193 | ||
N staging | 6.834 | 0.033 | |||
N0 | 114 | 34 | 148 | ||
N1 | 90 | 11 | 101 | ||
N2 | 67 | 11 | 78 | ||
Distant metastasis | 4.263 | 0.039 | |||
M0 | 235 | 54 | 289 | ||
M1 | 36 | 2 | 38 | ||
Lymphangion invasion | 0.006 | 0.578 | |||
Yes | 30 | 6 | 36 | ||
No | 241 | 50 | 291 | ||
Peripheral nerve infiltration | 0.254 | 0.615 | |||
Yes | 14 | 2 | 16 | ||
No | 257 | 54 | 311 |