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. 2015 Oct 15;8(10):19652–19661.

Table 1.

Univariate analysis results between hMLH1 protein expression and clinicopathological features

Normal hMLH1 (n=271) Aberrant hMLH1 (n=56) Total (n=327) χ2 P-value
Age (years) 0.439 0.507
    <50 66 16 82
    ≥50 205 40 245
Gender 0.184 0.668
    Male 168 33 201
    Female 103 23 126
Nationality 1.109 0.775
    Han 226 49 275
    Uyghur 26 4 30
    Hui 11 1 12
    Others 8 2 10
Tumor location 14.486 0.001
    Right hemicolon 46 22 68
    Left hemicolon 88 11 99
    Rectal 137 23 160
Tumor size (cm) 1.906 0.386
    <4 100 19 119
    4-6 103 18 121
    ≥6 68 19 87
Tissue type 10.487 0.005
    Glandular (well/moderately) 191 27 218
    Glandular (poorly) 33 11 44
    Mucous gland/signet cell 47 18 65
TNM staging 12.508 0.006
    I 26 5 31
    II 79 29 108
    III 130 20 150
    IV 36 2 38
T staging 1.620 0.655
    T1 15 2 17
    T2 32 6 38
    T3 62 17 79
    T4 162 31 193
N staging 6.834 0.033
    N0 114 34 148
    N1 90 11 101
    N2 67 11 78
Distant metastasis 4.263 0.039
    M0 235 54 289
    M1 36 2 38
Lymphangion invasion 0.006 0.578
    Yes 30 6 36
    No 241 50 291
Peripheral nerve infiltration 0.254 0.615
    Yes 14 2 16
    No 257 54 311