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. Author manuscript; available in PMC: 2015 Dec 29.
Published in final edited form as: Dev Biol. 2013 Jul 6;382(1):305–319. doi: 10.1016/j.ydbio.2013.06.029
Rules uniting ENC agents and growth cone agents
  1. Chemotaxis rule, whereby growth cones and ENC cells respond chemotactically to the same factors produced by the gut (see GDNF-bead attraction assays (Young et al., 2001).

  2. Gradient formation rule, whereby ENC cells consume this factor (consumption is already invoked to produce logistical growth; see above).