Skip to main content
. 2015 Dec 29;9(12):e0004279. doi: 10.1371/journal.pntd.0004279

Fig 7. Combinations of miconazole and RNAi have increased killing activity, suggesting that they function through inhibition of the same target.

Fig 7

(A) Schistosomula cultured with 10 μg/ml S. mansoni CYP450 dsRNA (black diamond); 2.5 μM miconazole (open circle); or 10 μg/ml S. mansoni CYP450 dsRNA and 2.5 μM miconazole (black circle). (B) Schistosomula cultured with 10 μg/ml S. mansoni CYP450 dsRNA (black diamond); 5 μM miconazole (black square); 5 μM miconazole plus 30 μg/ml irrelevant dsRNA and 5 μM miconazole (open circle); or 5 μM miconazole plus 10 μg/ml S. mansoni CYP450 dsRNA and 5 μM miconazole (black circle). All experiments were done in triplicate. Error bars indicate standard error of mean; *, p < 0.05; student t-test).