Table 3. Results with selected cytochrome P450 inhibitors used in this study.

Entry	Compound	Survival at 7 days (%)				Function and CYP450 class inhibited
		Adult		Schistosomula
		5 μM	10 μM	5 μM	10 μM
1	Miconazole	57	10	72	22	antifungal CYP51
2	Sertaconazole	95	15	65	6
3	Sulconazole	100	50	90	56
4	Fenticonazole	75	50	92	79
5	Econazole	100	55	87	66
6	Oxiconazole	100	60	89	71
7	Tioconazole	100	85	86	82
8	Bifoconazole	100	100	80	79
9	Butoconazole	100	80	77	60
10	Clotrimazole	n.d. 1	100	97	90
11	Ketoconazole	n.d.	100	98	97
12	Fluconazole	100	100	98	94
13	Posaconazole	100	100	94	88
14	Triadimenol	100	100	99	99
15	Prochloraz	100	100	94	82
16	Sulfaphenazole	100	100	99	93	antibacterial CYP2C9
17	Piperonyl butoxide	100	100	100	100	pesticide CYP6D1
18	Abiraterone acetate	100	100	100	100	prostate cancer CYP17A1
19	Anastrozole	100	100	100	100	breast cancer CYP19A1
20	Letrozole	100	100	100	100
21	Aminoglutethimide	100	100	100	100
22	Dafadine	100	100	100	100	CYP27A1

¹n.d., not determined.