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. 2015 Dec 29;10(12):e0145689. doi: 10.1371/journal.pone.0145689

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© 2015 Chrzanowska-Wodnicka et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 4 — Left: whole mount images. Right: (A, B, top row): Dilated microvessels in E10.5 EC-Rap1 KO embryo heads near neural tube (arrows). C-F: Control (Tie2-Cre⁰; Rap1a^f/f, Rap1b^f/f, E10.5) embryo sections. Blood-packed perineural vessels (C, D, arrows) are seen in fewer sections than in EC-Rap1KO embryos (B). (E, F, arrows) normal branchial arch arteries. Staining shown is H&E (A, C, E) and CD31 (B, D, F).