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. 2015 Sep 5;6(28):24611–24626. doi: 10.18632/oncotarget.5232

Figure 7. Validation of new p53 targets.

Figure 7

A. Overlap between p53-dependent up-regulated genes having a p53 binding site containing the unsplit motif in B and non-B cells. The percentages indicate the fraction of common DEGs for each cell type. B. Real-time RT-PCR analysis of B and non-B cells from control (mock) and irradiated (IR) Trp53+/+ and Trp53−/− mice shows p53-dependent up-regulation of the indicated genes. Slc22a12 could not be detected by Real-time RT-PCR. The reported values represent the average ± standard deviation of three biological replicates. *p < 0.05 (Student's t-test).