Table 2. Univariate and multivariate analysis of the relative risks for recurrence-free survival in HCC.
Variables | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
Relative risk | 95% CI | P | Relative risk | 95% CI | P | |
Age (>70 years) | 1.432 | 0.873–2.347 | 0.1547 | 1.758 | 0.744–4.155 | 0.2006 |
Sex (male) | 1.779 | 0.898–3.524 | 0.0986 | 2.371 | 0.807–6.966 | 0.1182 |
Liver cirrhosis | 1.147 | 0.695–1.895 | 0.5920 | |||
HBV infection | 0.949 | 0.563–1.597 | 0.8425 | |||
HCV infection | 1.439 | 0.890–2.328 | 0.1378 | 2.457 | 1.058–5.707 | 0.0375 |
V (+) | 1.299 | 0.824–2.048 | 0.2608 | |||
Tumor size (>30 mm) | 1.539 | 0.951–2.489 | 0.0793 | 1.503 | 0.619–3.649 | 0.3701 |
Pathology (contain por) | 0.446 | 0.165–1.199 | 0.1095 | 0.413 | 0.108–1.578 | 0.1981 |
Stage (≥3) | 1.318 | 0.840–2.067 | 0.2297 | |||
ALDH1A1 high expression | 0.739 | 0.471–1.158 | 0.1862 | 0.871 | 0.344–2.203 | 0.7714 |
AFP (>100 ng/ml) | 1.364 | 0.877–2.119 | 0.1681 | 3.502 | 1.332–9.203 | 0.0114 |
Albumin (≥3.5 g.dl) | 1.143 | 0.672–1.944 | 0.6221 | |||
Platelets (≥15 × 104/μl) | 1.019 | 0.644–1.612 | 0.9376 | |||
Total bilirubin (≥1.0 mg/dl) | 1.125 | 0.686–1.846 | 0.6412 |
Statistically significant values are displayed in boldface.
Abbreviations: HCC, hepatocellular carcinoma; CI, confidence interval; HBV, hepatitis B virus; HCV, hepatitis C virus; V, lymphovascular invasion; por, poorly differentiated; AFP, α-fetoprotein.