Table 1. Relationship between expression of ROR2 and Wnt5a tumor tissues and clinicopathological characteristics in NSCLC.
Groups | n | ROR2 expression | Wnt5a expression | ROR2+/Wnt5a+ expression | ||||||
---|---|---|---|---|---|---|---|---|---|---|
High(%) | Pearson χ2 | P | High (%) | Pearson χ2 | P | ROR2+/Wnt5a+(%) | Pearson χ2 | P | ||
Total | 219 | 109(49.77) | 78(35.62) | 57(26.00) | ||||||
Age | ||||||||||
≤ 60 years | 84 | 37(44.04) | 1.786 | 0.181 | 30(35.71) | 0.001 | 0.981 | 21(25.00) | 0.075 | 0.785 |
> 60 years | 135 | 72(53.33) | 48(35.56) | 36(26.67) | ||||||
Gender | ||||||||||
Male | 167 | 88(52.69) | 2.404 | 0.121 | 65(38.92) | 3.352 | 0.067 | 48(28.74) | 2.693 | 0.101 |
Female | 52 | 21(40.38) | 13(25.00) | 9(17.31) | ||||||
Differentiation | ||||||||||
Low grade | 48 | 25(52.08) | 0.016 | 0.898 | 21(43.75) | 0.910 | 0.340 | 15(31.25) | 0.403 | 0.526 |
Middle and high grade | 147 | 75(51.02) | 53(36.05) | 39(26.53) | ||||||
Others | 24 | 9 | 4 | 3 | ||||||
Histological type | ||||||||||
Adenocarcinoma | 118 | 66(55.93) | 0.127 | 0.722 | 47(39.83) | 0.286 | 0.593 | 35(29.66) | 0.280 | 0.597 |
Squamous cell carcinoma | 38 | 20(52.63) | 17(44.74) | 13(34.21) | ||||||
Othersa | 63 | 14 | 9 | |||||||
T | ||||||||||
Tis+T1 | 72 | 36(50.00) | 2.518 | 0.284 | 26(36.11) | 0.042 | 0.979 | 18(25.00) | 0.135 | 0.935 |
T2 | 123 | 59(47.97) | 44(35.77) | 33(26.83) | ||||||
T3+T4 | 21 | 14(66.67) | 8(38.10) | 6(28.57) | ||||||
Unknown | 3 | 0 | 0 | |||||||
N | ||||||||||
N0 | 120 | 54(45.00) | 2.581 | 0.275 | 37(30.83) | 2.720 | 0.257 | 26(21.67) | 2.874 | 0.238 |
N1 | 54 | 29(53.70) | 23(42.59) | 18(33.33) | ||||||
N2 | 45 | 26(57.78) | 18(40.00) | 13(28.89) | ||||||
TNM stage | ||||||||||
0-I | 89 | 35(39.33) | 7.627 | 0.022* | 23(25.84) | 7.011 | 0.030* | 14(15.73) | 9.287 | 0.010* |
II | 72 | 41(56.94) | 32(44.44) | 26(36.11) | ||||||
III-IV | 55 | 33(60.00) | 23(41.82) | 17(30.91) | ||||||
Unknown | 3 | 0 | 0 |
P < 0.05
others, Adenosquamous carcinoma and others.