Table 2. Apoptosis effect of EpAb2-6 in cancerous or normal cells.
Cancer type (cell line) | Antibody | Concentration tested (μg/ml) | |||||
---|---|---|---|---|---|---|---|
0 | 0.1 | 1 | 5 | 10 | 20 | ||
Oral cancer(SAS) | EpAb2-6 | 13.84 | 20.91 | 27.56 | 40.56 | 43.89 | 50.4 |
NM-IgG | 14.82 | 13.08 | 14.05 | 12.24 | 10.93 | 10.99 | |
Colon cancer(HCT116 (TP53+/+)) | EpAb2-6 | 11.1 | 14.12 | 30.82 | 42.18 | 51.7 | 52.26 |
NM-IgG | 12.5 | 8.82 | 8.08 | 12.06 | 10.22 | 9.54 | |
Colon cancer(HCT116 (TP53−/−)) | EpAb2-6 | 9.45 | 25.81 | 32.67 | 40.77 | 56.66 | 55.5 |
NM-IgG | 12.82 | 11.97 | 12.99 | 17.14 | 13.69 | 13.95 | |
Normal nasal mucosal epithelia(NNM) | EpAb2-6 | 9.54 | 9.12 | 8.49 | 9.55 | 8.77 | 11.5 |
NM-IgG | 10.69 | 9.51 | 8.21 | 9.56 | 9.4 | 10.2 |