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. 2015 Aug 6;6(28):24947–24968. doi: 10.18632/oncotarget.4453

Table 2. Apoptosis effect of EpAb2-6 in cancerous or normal cells.

Cancer type (cell line) Antibody Concentration tested (μg/ml)
0 0.1 1 5 10 20
Oral cancer(SAS) EpAb2-6 13.84 20.91 27.56 40.56 43.89 50.4
NM-IgG 14.82 13.08 14.05 12.24 10.93 10.99
Colon cancer(HCT116 (TP53+/+)) EpAb2-6 11.1 14.12 30.82 42.18 51.7 52.26
NM-IgG 12.5 8.82 8.08 12.06 10.22 9.54
Colon cancer(HCT116 (TP53−/−)) EpAb2-6 9.45 25.81 32.67 40.77 56.66 55.5
NM-IgG 12.82 11.97 12.99 17.14 13.69 13.95
Normal nasal mucosal epithelia(NNM) EpAb2-6 9.54 9.12 8.49 9.55 8.77 11.5
NM-IgG 10.69 9.51 8.21 9.56 9.4 10.2