Table 1. Hepatocellular carcinoma associated microRNAs.
microRNA | Chromosome | Permutation p-value | Corrected p-value | No. of Studies | Seed family | microRNA Cluster |
---|---|---|---|---|---|---|
Upregulated | ||||||
miR-93-5p | 7q22.1 | 1.55E–10 | 3.23E–05 | 12 | miR-17/17-5p/20ab/20b-5p/93/106ab/427/518a-3p/519d | miR-25/miR-93/miR-106 |
miR-224-5p | Xq28 | 5.85E–14 | 1.22E–08 | 12 | miR-224 | miR-224/miR-452 |
miR-222-3p | Xp11.3 | 5.81E–14 | 1.21E–08 | 12 | miR-221/222/222ab/1928 | miR-221/miR-222 |
miR-221-3p | Xp11.3 | 7.10E–17 | 1.48E–11 | 16 | miR-221/222/222ab/1928 | miR-221/miR-222 |
miR-21-5p | 17q23.1 | 3.65E–12 | 7.63E–07 | 15 | miR-21/miR-590-5p | - |
Downregulated | ||||||
miR-223-3p | Xq12 | 2.59E–09 | 5.40E–04 | 9 | miR-223 | - |
miR-214-3p | 1q24.3 | 1.01E–13 | 2.11E–08 | 13 | miR-214/761/3619-5p | miR-199/miR-214 |
miR-199a-5p | 19p13.2/1q24.3 | 2.95E–19 | 6.17E–14 | 14 | miR-199a-5p | - |
miR-199a-3p | 19p13.2/1q24.3 | 1.20E–16 | 2.52E–11 | 15 | miR-199ab-3p/3129-5p | - |
miR-195-5p | 17p13.1 | 1.85E–11 | 3.86E–06 | 14 | miR-15abc/16/16abc/195/322/424/497/1907 | miR-195/miR-497 |
miR-150-5p | 19q13.33 | 2.60E–09 | 5.44E–04 | 10 | miR-150/5127 | - |
miR-145-5p | 5q32 | 4.90E–12 | 1.02E–06 | 13 | miR-145 | miR-143/miR-145 |
miR-130a-3p | 11q12.1 | 3.13E–09 | 6.55E–04 | 9 | miR-130ac/301ab/301b/301b-3p/454/721/4295/3666 | miR-130/miR-301/miR-454 |