Figure 3. Changes in high- and low-molecular-weight hnRNP K protein expression in bortezomib-treated human Burkitt's lymphoma cells.

(A, B) Daudi cells were treated with A. various concentrations of bortezomib (Bz) for 12 h, or B. 10 nM bortezomib for the indicated periods. Total cellular proteins were collected to detect protein expression by western blotting. HMw, high-molecular-weight; LMw, low-molecular-weight. The numbers below the lanes indicate the relative intensities of HMw to control (defined as 1.0) proteins.