Table 2. In vitro salisphere formation and in vivo tumorigenic potential of cells selected by the following putative CSC marker combinations.
ALDH/CD44 | Salisphere Formation | In Vivo Tumorigenicity | ||
---|---|---|---|---|
UM-HMC-3A | UM-HMC-3B | Low-Passage | High-Passage | |
High/High | High | High | High | High |
High/Low | NA | NA | NA | NA |
Low/High | High | High | NA | NA |
Low/Low | Low | Low | Low | Low |
CD10/CD44 | ||||
High/High | Low | High | NA | Low |
High/Low | Low | Intermediate | NA | Low |
Low/High | Intermediate | Intermediate | NA | None |
Low/Low | High | Low | NA | None |
CD44/CD24 | ||||
High/High | Low | Low | Low | High |
High/Low | Intermediate | Low | Low | Low |
Low/High | Intermediate | High | High | Low |
Low/Low | High | Low | Low | Intermediate |
CD10/CD44 | ||||
High/High | Intermediate | High | None | NA |
High/Low | Low | NA | NA | NA |
Low/High | High | Intermediate | NA | NA |
Low/Low | Low | NA | Low | NA |