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. 2015 Aug 10;6(29):26971–26981. doi: 10.18632/oncotarget.4699

Figure 3. Diagnostic and prognostic values of exosomal miR-21 levels in glioma patients.

Figure 3

A. Receiver operation Characterization (ROC) curves based on exosomal miR-21 levels to differentiate recurrent glioma patients (n = 70) from non-tumor diseases. The area under curve (AUC) was as 0.927 (95% CI: 0.865–0.985). The ROC curves to discriminate low grade (Grade II) glioma and high grade (Grade IV or Grade III) cases were shown in B and C. with the AUC of 0.872 (95% CI: 0.817–0.927) and 0.751 (95% CI: 0.681–0.821), respectively. D and E. Kaplan-Meier survival statistics using microarray detection of tissue miR-21 abundance for glioma prognosis (n = 198, from CGGA).