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. 2015 Aug 21;6(29):27427–27439. doi: 10.18632/oncotarget.4861

Figure 1. DAB2IP KD promotes proliferation, invasion and EMT in CRC cells.

Figure 1

A. DAB2IP expression in SW480 and HCT116 cell lines transfected with two specific shRNAs toward DAB2IP by real-time PCR. B. Effect of DAB2IP KD on the proliferation of SW480 and HCT116 cells by MTT assay. C. Effect of DAB2IP KD on cell cycle of SW480 and HCT116 cells by Flow Cytometry. D. Effect of DAB2IP KD on the invasion of SW480 and HCT116 cells by Boyden chamber. Scale bars represent 50 μm. E. Immunofluorescence analyses of E-cadherin and Vimentin in DAB2IP KD cells. Representative morphologic transition was also shown. Scale bars represent 10 μm. F. The expressions of E-cadherin, α-catenin and Vimentin in DAB2IP KD SW480 and HCT116 cells by Western blotting.