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. 2015 Jun 25;6(29):27478–27489. doi: 10.18632/oncotarget.4393

Figure 4. STAT3 activation is enhanced in melanoma tissues of mice treated with Bay60-6583.

Figure 4

A and B. phospho-STAT3 (pSTAT3) protein expression analysis in melanoma tissues of mice treated with Bay60-6583 or vehicle (ctr), receiving the STAT3 inhibitor S3I-201 5mg/kg i.p. or vehicle. C. VEGF protein expression analysis in melanoma tissues of mice treated with Bay60-6583 or vehicle and receiving the STAT3 inhibitor S3I-201. D. Melanoma volume was monitored during the treatment with S3I-201 in mice receiving Bay60-6583 or vehicle. Data are from three independent experiments and represent mean ± SEM (n = 6–12) *p < 0.05, **p < 0.01 and°°°p < 0.001.