Table 1. Association of NEAT1 expression with clinical features.
Variable | n | NEAT1 expression | P | |
---|---|---|---|---|
Low | High | |||
Total | 239 | 129 | 110 | |
Sex | 0.771* | |||
Male | 141 | 75 | 66 | |
Female | 98 | 54 | 44 | |
Age at diagnosis | 0.736* | |||
≤60 | 144 | 79 | 65 | |
>60 | 95 | 50 | 45 | |
Tumor site | ||||
Left colon | 68 | 36 | 32 | 0.389* |
Right colon | 78 | 38 | 40 | |
Rectum | 93 | 55 | 38 | |
Tumor size | 0.117* | |||
≤3.0 cm | 82 | 50 | 32 | |
>3.0 cm | 157 | 79 | 78 | |
Differentiation status | 0.011* | |||
Well | 41 | 31 | 10 | |
Moderately | 103 | 62 | 41 | |
Poor | 95 | 46 | 49 | |
Depth of invasion | 0.040* | |||
T1+ T2 | 92 | 57 | 35 | |
T3+ T4 | 147 | 71 | 76 | |
Lymph node metastasis | 0.026* | |||
Absent | 92 | 58 | 34 | |
Present | 147 | 71 | 76 | |
Distant metastasis | 0.027* | |||
Absent | 208 | 118 | 90 | |
Present | 31 | 11 | 20 | |
TNM stage | 0.026* | |||
I+II | 92 | 58 | 34 | |
III+IV | 147 | 71 | 76 | |
MSI | 0.285* | |||
MSS | 200 | 111 | 89 | |
MSI-H | 39 | 18 | 21 | |
APC mutation | 0.227* | |||
(−) | 151 | 86 | 65 | |
(+) | 88 | 43 | 45 | |
KRAS mutation | 0.251* | |||
(−) | 159 | 90 | 69 | |
(+) | 80 | 39 | 41 | |
BRAF mutation | 0.112* | |||
(−) | 197 | 111 | 86 | |
(+) | 42 | 18 | 24 | |
PIK3CA mutation | 0.154* | |||
(−) | 204 | 114 | 90 | |
(+) | 35 | 15 | 20 |
P value when expression levels were compared using Pearson χ2 test