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. 2015 Jul 20;6(29):28011–28025. doi: 10.18632/oncotarget.4377

Figure 1. TUDCA prevents the development of HCC during carcinogen exposure.

Figure 1

A. Representative images of livers treated for 25 weeks with the indicated treatments. B. Quantitative analysis of the tumor burden as assessed by C. Reticulin staining. Scale bar: 100 μm. D. 18F-Choline positron emission tomography was performed to visualize cell membrane synthesis after the indicated treatments (blue: low, red: high activity). E. Quantification of 18F-Choline positron emission tomography. Standardized uptake values of the mouse livers are presented as the mean ± SD. One-way ANOVA was applied for statistical analysis. *p < 0.05, **p < 0.01.