Table 1. Mouse body weight (g) (mean ± SD).
| Group | Average body weight 25 weeks (g) | Average body weight 30 weeks (g) | Survival (%) |
|---|---|---|---|
| Preventive study | |||
| Saline | 31.22 ± 1.39 | 100 | |
| DEN + control | 26.75 ± 1.96*** | 75 | |
| DEN + low dose TUDCA | 27.39 ± 1.45# | 83 | |
| DEN + high dose TUDCA | 24.64 ± 2.17# | 67 | |
| Therapeutic study | |||
| DEN ⇒ control | 25.96 ± 3.65 | 22.92 ± 3.19 | 67 |
| DEN ⇒ low dose TUDCA | 23.86 ± 2.70 | 22.13 ± 2.57¥ | 75 |
| DEN ⇒ high dose TUDCA | 24.53 ± 2.13 | 23.43 ± 2.61¥ | 67 |
***
p < 0.001: 25 weeks DEN vs. saline.
#
not significant compared to DEN + control.
¥
not significant compared to DEN ⇒ control.
DEN, diethylnitrosamine.