Table 2. Characteristics of MET exon 14 deletion (METex14) patients according to tumor types.
| Colon | Gastric | ACUP | Lung | |
|---|---|---|---|---|
| N | 4 | 3 | 1 | 5 |
| Age | ||||
| Median | 63 | 53 | 49 | |
| (range) | 42–87 | 27–67 | 36–60 | |
| Gender | ||||
| Male | 2 | 2 | 1 | 1 |
| Female | 2 | 1 | 0 | 4 |
| Smoking history | ||||
| Never-smoker | NC | NC | NC | 4 |
| Ever-smoker | 1 | |||
| Histology | ||||
| Adenocarcinoma | 4 | 3 | 1 | 4 |
| Squamous cell | 0 | 0 | 0 | 1 |
| Large cell neuroendocrine | 0 | 0 | 0 | 0 |
| Undifferentiated | 0 | 0 | 0 | 0 |
| Tumor differentiation | ||||
| Well | 1 | 0 | 0 | 0 |
| Moderate | 2 | 0 | 0 | 1 |
| Poor | 1 | 3 | 1 | 4 |
| MET IHC | ||||
| 0 | 0 | 0 | 0 | 0 |
| 1+ | 0 | 0 | 0 | 0 |
| 2+ | 1 | 0 | 0 | 0 |
| 3+ | 3 | 3 | 1 | 5 |
| Concomitant MET amplification | ||||
| Yes | 0 | 1 | 0 | 0 |
| No | 4 | 2 | 0 | 5 |
| Confirmed by RT-PCR | ||||
| Yes | 4 | 3 | 1 | 5 |
| No | 0 | 0 | 0 | 0 |
NC, not contributable; wt, wild type.