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A and B. TCF4-reporter assays after knockdown of DDX3 with 50 nM siDDX3 (A) and inhibition of DDX3 with RK-33 (B) in DDX3-dependent colorectal cancer cell lines HCT116 and HT29. C and D. Relative mRNA expression of TCF4-target genes after knockdown of DDX3 with 50 nM siDDX3 (C) or DDX3 inhibition with RK-33 (D). All experiments were performed three independent times, graphs represent mean ± SD, *p < 0.05, **p < 0.01.
