Table 1. Clinicopathological characteristics of DDX3 low and DDX3 high colorectal cancers.
| Total | Low DDX3 | High DDX3 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n | % | n | % | n | % | P-value | RR | 95% CI | ||
| Total | 303 | 100.0 | 179 | 59.1% | 124 | 40.9% | ||||
| Sex | Male | 169 | 55.8% | 102 | 57.0% | 67 | 54.0% | 0.61 | 1.08 | 0.84–1.39 |
| Female | 134 | 44.2% | 77 | 43.0% | 57 | 46.0% | ||||
| TNM stage | 1 | 22 | 9.6% | 13 | 9.7% | 9 | 9.4% | 0.73 | ||
| 2 | 98 | 42.6% | 54 | 40.3% | 44 | 45.8% | ||||
| 3 | 80 | 34.8% | 47 | 35.1% | 33 | 34.4% | ||||
| 4 | 30 | 13.0% | 20 | 14.9% | 10 | 10.4% | ||||
| Differentiation grade | Well | 16 | 5.3% | 8 | 4.5% | 8 | 6.5% | 0.62 | ||
| Moderate | 228 | 75.7% | 134 | 75.3% | 94 | 76.4% | ||||
| Poor | 57 | 18.9% | 36 | 20.2% | 21 | 17.1% | ||||
| Site of origin | Rectum | 95 | 31.4% | 56 | 31.3% | 39 | 31.5% | 0.98 | 1.00 | 0.85–1.16 |
| Colon | 208 | 68.6% | 123 | 68.7% | 85 | 68.5% | ||||
| Tumor size | <40 mm | 49 | 22.0% | 24 | 19.0% | 25 | 25.8% | 0.44 | ||
| 40–60 mm | 120 | 53.8% | 69 | 54.8% | 51 | 52.6% | ||||
| >60 mm | 54 | 24.2% | 33 | 26.2% | 21 | 21.6% | ||||
| Age at time of diagnosis | <65 years | 82 | 27.1% | 54 | 30.2% | 28 | 22.6% | 0.25 | ||
| 65–80 years | 167 | 55.1% | 92 | 51.4% | 75 | 60.5% | ||||
| >80 years | 54 | 17.8% | 33 | 18.4% | 21 | 16.9% | ||||
| Surgical margins | negative | 230 | 99.1% | 135 | 100.0% | 95 | 97.9% | 0.17 | ||
| positive | 2 | 0.9% | 0 | 0.0% | 2 | 2.1% | ||||
Baseline characteristics of colorectal cancer patients with low and high DDX3 expression. P-values are determined by a chi-square test.