Skip to main content
. 2015 Jul 22;6(29):28371–28388. doi: 10.18632/oncotarget.4948

Figure 9. Analysis of the single nucleotide-resolution peak enriched for p53 mRNA.

Figure 9

RNAs from AGO2-associated RNP were sequenced, and the obtained RNA fragment sequences were mapped to the p53 mRNA sequence (GenBank: JN900492.1). A. Regional distribution analysis of RNA fragments from anti-AGO2 RNP complexes. B. Peak enrichment in various regions of p53 mRNA. C. The peak located between nt1738 and nt1746 of p53 mRNA is a potential miR-150 binding site, and the peak located between nt1899 and nt1907 is the potential binding site of let-7. The peak between nt2050 and nt057 is a potential miR-22-3p binding site. The peak between nt2146 and nt2154 is a potential VTRNA2-1-5p binding site within the 3′-UTR of p53 mRNA. TSS = transcription start site; TES = transcription termination site.