Table 2. Hemodynamic variables at time points t 1 through t 4.
All (n = 12) | Diabetics (n = 5) | Non-Diabetics (n = 7) | p+ | |
---|---|---|---|---|
MAP (mmHg) | ||||
t1 | 114 .2 ± 16.8 | 116.0 ± 3.4 | 112.9 ± 22.4 | 0.77 |
t2 | 110.4 ± 16.9 | 114.9 ± 9.2 | 107.2 ± 20.9 | 0.46 |
t3 | 109.7 ± 23.1 | 115.6 ± 26.4 | 105.5 ± 21.5 | 0.48 |
t4 | 111.7 ± 22.4 | 116.8 ± 18.9 | 108.1 ± 25.4 | 0.53 |
p* | 0.71 | 0.99 | 0.14 | |
HR (1/min) | ||||
t1 | 70.5 ± 11.4 | 65.5 ± 14.5 | 74.0 ± 7.9 | 0.22 |
t2 | 69.6 ± 12.9 | 64.7 ± 14.7 | 73.2 ± 11.3 | 0.28 |
t3 | 69.3 ± 13.3 | 64.0 ± 18.7 | 73.1 ± 7.3 | 0.26 |
t4 | 72.1 ± 15.2 | 66.2 ± 22.1 | 76.3 ± 6.7 | 0.28 |
p* | 0.82 | 0.89 | 0.49 | |
Hct (%) | ||||
t1 | 35.13 ± 2.13 | 35.73 ± 2.51 | 34.70 ± 1.90 | 0.44 |
t2 | 35.67 ± 2.18 | 36.29 ± 2.70 | 35.22 ± 1.81 | 0.43 |
t3 | 35.62 ± 1.83 | 35.52 ± 2.40 | 35.69 ± 1.51 | 0.88 |
t4 | 36.72 ± 2.01 | 37.57 ± 2.38 | 36.11 ± 1.62 | 0.23 |
p* | 0.003 | 0.17 | < 0.001 | |
Vp (L) | ||||
t1 | 3.65 ± 0.77 | 3.03 ± 0.82 | 4.09 ± 0.29 | 0.009 |
t2 | 3.48 ± 0.81 | 2.99 ± 0.85 | 3.84 ± 0.62 | 0.07 |
t3 | 3.55 ± 0.83 | 2.96 ± 0.85 | 3.98 ± 0.52 | 0.03 |
t4 | 3.40 ± 0.78 | 2.86 ± 0.82 | 3.79 ± 0.49 | 0.03 |
p* | 0.008 | 0.03 | 0.03 | |
QI (L/min/m2) | ||||
t1 | 0.61 ± 0.22 | 0.47 ± 0.13 | 0.72 ± 0.23 | 0.06 |
t2 | 0.56 ± 0.19 | 0.43 ± 0.15 | 0.66 ± 0.18 | 0.04 |
t3 | 0.54 ± 0.22 | 0.39 ± 0.14 | 0.64 ± 0.21 | 0.04 |
t4 | 0.52 ± 0.20 | 0.39 ± 0.15 | 0.61 ± 0.19 | 0.07 |
p* | 0.003 | 0.001 | p = 0.07 | |
ICG-DR (%/min) | ||||
t1 | 19.3 ± 6.2 | 16.2 ± 4.2 | 21.5 ± 6.6 | 0.15 |
t2 | 18.8 ± 5.8 | 15.8 ± 4.2 | 20.9 ± 6.0 | 0.14 |
t3 | 18.3 ± 5.5 | 15.7 ± 4.2 | 20.2 ± 5.8 | 0.17 |
t4 | 18.2 ± 5.2 | 15.8 ± 4.5 | 19.9 ± 5.3 | 0.19 |
p* | 0.001 | 0.29 | 0.002 | |
RI (mmHg∙s∙m2/mL) | ||||
t1 | 12.40 ± 4.21 | 15.71 ± 4.23 | 10.03 ± 2.21 | 0.01 |
t2 | 13.30 ± 5.43 | 17.64 ± 5.85 | 10.19 ± 2.06 | 0.01 |
t3 | 14.27 ± 6.18 | 19.65 ± 5.99 | 10.43 ± 2.19 | 0.004 |
t4 | 14.94 ± 6.36 | 20.29 ± 6.46 | 11.11 ± 2.29 | 0.005 |
p* | 0.001 | 0.01 | 0.18 |
n: number of subjects; MAP: mean arterial pressure; HR: heart rate: Hct: hematocrit: Vp: plasma volume: QI: hepato-splanchnic blood flow index: ICG-DR, Indocyanine green disappearance rate: RI, hepato-splanchnic vascular resistance index; p*: probability for single factor variance analyses with repeated measurement; p +: probability for two sample t-test for comparison between diabetics and non-diabetics