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. 2015 Dec 29;10(12):e0145411. doi: 10.1371/journal.pone.0145411

Table 2. Hemodynamic variables at time points t 1 through t 4.

All (n = 12) Diabetics (n = 5) Non-Diabetics (n = 7) p+
MAP (mmHg)
t1 114 .2 ± 16.8 116.0 ± 3.4 112.9 ± 22.4 0.77
t2 110.4 ± 16.9 114.9 ± 9.2 107.2 ± 20.9 0.46
t3 109.7 ± 23.1 115.6 ± 26.4 105.5 ± 21.5 0.48
t4 111.7 ± 22.4 116.8 ± 18.9 108.1 ± 25.4 0.53
p* 0.71 0.99 0.14
HR (1/min)
t1 70.5 ± 11.4 65.5 ± 14.5 74.0 ± 7.9 0.22
t2 69.6 ± 12.9 64.7 ± 14.7 73.2 ± 11.3 0.28
t3 69.3 ± 13.3 64.0 ± 18.7 73.1 ± 7.3 0.26
t4 72.1 ± 15.2 66.2 ± 22.1 76.3 ± 6.7 0.28
p* 0.82 0.89 0.49
Hct (%)
t1 35.13 ± 2.13 35.73 ± 2.51 34.70 ± 1.90 0.44
t2 35.67 ± 2.18 36.29 ± 2.70 35.22 ± 1.81 0.43
t3 35.62 ± 1.83 35.52 ± 2.40 35.69 ± 1.51 0.88
t4 36.72 ± 2.01 37.57 ± 2.38 36.11 ± 1.62 0.23
p* 0.003 0.17 < 0.001
Vp (L)
t1 3.65 ± 0.77 3.03 ± 0.82 4.09 ± 0.29 0.009
t2 3.48 ± 0.81 2.99 ± 0.85 3.84 ± 0.62 0.07
t3 3.55 ± 0.83 2.96 ± 0.85 3.98 ± 0.52 0.03
t4 3.40 ± 0.78 2.86 ± 0.82 3.79 ± 0.49 0.03
p* 0.008 0.03 0.03
QI (L/min/m2)
t1 0.61 ± 0.22 0.47 ± 0.13 0.72 ± 0.23 0.06
t2 0.56 ± 0.19 0.43 ± 0.15 0.66 ± 0.18 0.04
t3 0.54 ± 0.22 0.39 ± 0.14 0.64 ± 0.21 0.04
t4 0.52 ± 0.20 0.39 ± 0.15 0.61 ± 0.19 0.07
p* 0.003 0.001 p = 0.07
ICG-DR (%/min)
t1 19.3 ± 6.2 16.2 ± 4.2 21.5 ± 6.6 0.15
t2 18.8 ± 5.8 15.8 ± 4.2 20.9 ± 6.0 0.14
t3 18.3 ± 5.5 15.7 ± 4.2 20.2 ± 5.8 0.17
t4 18.2 ± 5.2 15.8 ± 4.5 19.9 ± 5.3 0.19
p* 0.001 0.29 0.002
RI (mmHg∙s∙m2/mL)
t1 12.40 ± 4.21 15.71 ± 4.23 10.03 ± 2.21 0.01
t2 13.30 ± 5.43 17.64 ± 5.85 10.19 ± 2.06 0.01
t3 14.27 ± 6.18 19.65 ± 5.99 10.43 ± 2.19 0.004
t4 14.94 ± 6.36 20.29 ± 6.46 11.11 ± 2.29 0.005
p* 0.001 0.01 0.18

n: number of subjects; MAP: mean arterial pressure; HR: heart rate: Hct: hematocrit: Vp: plasma volume: QI: hepato-splanchnic blood flow index: ICG-DR, Indocyanine green disappearance rate: RI, hepato-splanchnic vascular resistance index; p*: probability for single factor variance analyses with repeated measurement; p +: probability for two sample t-test for comparison between diabetics and non-diabetics