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. 2015 Jun 30;6(27):23157–23180. doi: 10.18632/oncotarget.4319

Figure 2. Prognostic significance of c-Rel nuclear expression in various DLBCL subsets.

Figure 2

A–B. In the overall- and GCB-DLBCL, c-Rel positivity did not correlate with patient survival. C. In ABC-DLBCL, c-Rel+ as a univariate did not correlate significantly with patient survival although a trend toward poorer survival was suggested. D. In Bcl-2− (<70%) ABC-DLBCL, c-Rel+ correlated with significantly poorer patient survival. E–F. c-Rel+ concurrent with p50 or p65 expression correlated with poorer patient survival with marginal P values. G–I. In DLBCL with MUT-p53 but not WT-p53, c-Rel+ correlated with significantly poorer patient survival. J. In ABC-DLBCL with c-Rel nuclear expression, p63 expression correlated with significantly better patient survival. K–L. Only in p63− but not p63+ ABC-DLBCL subcohort, c-Rel positivity correlated with significantly poorer patient survival. Abbreviations: OS, overall survival; PFS, Progression-free survival.