Table 2. DMD patients.
Age at Biopsy (y) | Muscle type | Dystrophin | CK U/L | % of utrophin fibers | Clinical data |
---|---|---|---|---|---|
3 | QF | absent | 4156 | 48 | Calf hypertrophy, Gowers' sign, difficulty in climbing stairs |
4 | QF | Few RFs | 14000 | 59 | Calf hypertrophy |
5 | QF | absent | 23000 | 73 | Calf hypertrophy, Gowers' sign, waddling gait, proximal weakness |
8 | QF | absent | 14000 | 70 | Gowers' sign, waddling gait |
9 | QF | absent | 5500 | 73 | Unable to raise from floor, tip-toe walking, upper limb weakness |
9 | QF | absent | 9000 | 61 | Calf hypertrophy, waddling gait, Joint contractures, Gowers' sign |
CK- creatine kinase, QF - quadriceps femoris.