Table 1. Association of 4E-BP1 expression and clinical parameters in tumor tissues of colorectal cancer patients.
| Parameters | 4E-BP1 | p value | |
|---|---|---|---|
| Low | High | ||
| (n = 98) (%) | (n = 94) (%) | ||
| Age (years) | |||
| ≦65 | 51 (52.0) | 43 (45.7) | |
| >65 | 47 (48.0) | 51 (54.2) | 0.391 |
| Gender | |||
| Female | 39 (39.8) | 51 (54.3) | |
| Male | 59 (60.2) | 43 (45.7) | 0.060 |
| T factor | |||
| 1 | 5 (5.1) | 2 (2.1) | |
| 2 | 15 (15.3) | 13 (13.8) | |
| 3 | 55 (56.1) | 55 (58.5) | |
| 4 | 23 (23.5) | 24 (25.5) | 0.713 |
| N factor | |||
| 0 | 50 (51.0) | 33 (35.1) | |
| 1+2 | 48(49.0) | 61 (64.9) | 0.029 |
| M factor | |||
| 0 | 83 (84.7) | 76 (80.9) | |
| 1 | 15 (15.3) | 18 (19.1) | 0.567 |
| Stage | |||
| I | 13 (13.3) | 10 (10.6) | |
| II | 33 (33.7) | 20 (21.3) | |
| III | 36 (36.7) | 46 (48.9) | |
| IV | 16 (16.3) | 18 (19.1) | 0.184 |
| Stage | |||
| Early | 46 (46.9) | 29 (30.9) | |
| Late | 52 (53.1) | 65 (69.1) | 0.027 |
No positive or only one positively stained section was defined as “low” expression of 4E-BP1, and the presence of at least two positively stained sections was classified as “high” expression. (N = 192).