Figure 7. Short-chain ceramides induce ceramide accumulation and apoptosis for PEL cells.

A.–B. BCBL-1 cells were incubated with the indicated concentrations of C2-Cer, C6-Cer, C8-Cer or vehicle for 24 h, then apoptosis quantified as described previously. C. Intracellular ceramide and dh-ceramide species were quantified as above. Error bars represent the S.E.M. for 2 independent experiments, * = p < 0.05; ** = P < 0.01.